MedCalc is a stand-alone computer program for statistics in the biomedical sciences with an integrated spreadsheet for easy data input. It can import Excel, SPSS, DBase and Lotus files, and files in SYLK, DIF or text format. Special features of the program are, amongst others, lots of graphs including ROC curves, Kaplan-Meier survival plots, Bland & Altman plot, Deming and Passing & Bablok regression for method comparison.